Description
Product Characteristics:
Aliases: Alpha Pix antibody, Alpha-Pix antibody, ARHG6_HUMAN antibody, ARHGEF6 antibody, COOL 2 antibody, COOL-2 antibody, COOL2 antibody, Mental retardation, X linked 46 antibody, MRX46 antibody, PAK interacting exchange factor alpha antibody, PAK-interacting exchange factor alpha antibody, PIXA antibody, Rac/Cdc42 guanine exchange factor (GEF) 6 antibody, Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antibody, Rac/Cdc42 guanine nucleotide exchange factor 6 antibody, Rho guanine nucleotide exchange factor 6 antibody
Target Information: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq, Jul 2008]